Publications ( In reverse chronological order)
- Claude Bernard -
“The joy of discovery is certainly the liveliest that the mind of man can ever feel”

49. 2-aryl benzimidazole conjugate induced apoptosis in human breast cancer MCF-7 cells through caspase independent pathway. (2016) V. Lakshma Nayak, Narayana Nagesh, A. Ravikumar, Chandrakant Bagul, M.V.P.S. Vishnuvardhan, Vunnam Srinivasulu, Ahmed Kamal. Apoptosis. (Accepted).
48. Synthesis, DNA binding affinity and anticancer activity of novel 4H-benzo[g][1,2,3]triazolo[5,1-c][1,4]oxazocines. (2016) K. N. Visweswara Sastry, Sunitha Routhu, Soma Gupta Datta, Narayana Nagesh,* Bathini Nagendra Babu, Jagadeesh Babu Nanubolu, C. Ganesh Kumar,Ram Awatar Maurya*and Ahmed Kamal*. Organic Biomolecular Chemistry, 14, 9294–9305.
47. Benzo[b]furan derivatives induces apoptosis by targeting the PI3K/Akt/ mTOR signaling pathway in human breast cancer cells. (2016) Ahmed Kamal, V. Lakshma Nayak, Narayana Nagesh, M.V.P.S. Vishnuvardhan, N.V. Subba Reddy. Bioorganic Chemistry, DOI: 10.1039/ C6CE00139D .
46. Association of mitochondrial displacement looppolymorphisms with risk of colorectal cancer insouth Indian population (2016) Suresh Govatati, Bulle Saradamma, Sravanthi Malempati, DivyamaanasaDasi, Murali Krishna Thupurani, Narayana Nagesh, Sisinthy Shivaji, ManjulaBhanoori, Raghava Rao Tamanam, Varadacharyulu Nallanchakravarthula, Sreenivasa Rao Pasupuleti, Mitochondrial DNA (Part A), DOI; 10.3109/24701394.2016.1160076.
45. Anticancer activity of large metalla-assemblies built from half-sandwich complexes.( 2016) Gajendra Gupta, Gopi Suresh Oggu, Nagesh Narayana, Kiran Kumar Bokara and Bruno Therrien, CrystEngComm. DOI: 10.1039/C6CE00139D.
44. Manganese-superoxide dismutase (Mn-SOD) overexpression is a common event in colorectal cancers with mitochondrial microsatellite instability.(2016) Suresh Govatati, Sravanthi Malempati,Bulle Saradamma, Dasi Divyamaanasa,B. Prathap Naidu,Pallaval Veera Bramhachari, Nagesh Narayana,Sisinthy Shivaji, Manjula Bhanoori,Raghava Rao Tamanam,Pasupuleti Sreenivasa Rao, Varadacharyulu Nallanchakravarthula,Tumor Biology ( DOI: 10.1007/s13277-016-4918-0).
43. Identification and characte- rization of stressed degrada- tion products of rabeprazole using LC /ESI / MS /MS and 1H-NMR experiments: In vitrotoxicity evaluation of major degradation products. (2016) Murali Mohan Bhandi, Roshan M. Borkar, G. Shankar, Snehal Raut, Narayana Nagesh and R. Srinivas, RSC Advances, 6, 10719-10735.
42. Design and synthesis of C3-tethered 1,2,3-triazolo-β-carboline derivatives: Anticancer activity, DNA-binding ability, viscosity and molecular modeling studies.(2016) Nagula Shankaraiah, Chetna Jadala, Shalini Nekkanti, Kishna Ram Senwar , Narayana Nagesh , Shweta Shrivastava, V. G. M. Naidu, Manda Sathish, Ahmed Kamal*, Bioorganic Chemistry, 64, 42-50.
41. Phenotypic Variations in the 22q11 Deletion Syndrome—Studyin a South Indian Population. (2015) Satish V.S.S. Pilli, D. Anuradha, N.Manoj, N. Nagesh, Raghavannair Suresh Kumar, Gopala Krishna Aradhyam, Indian J Pediatrics, DOI : 10.1007/s12098-015-1954-5.
40. Sugar-boronate ester scaffold tethered pyridyl -imine palladium(II) complexes:Synthesis and their in vitro anticancer evaluation. (2015)
Eda Rami Reddy, Rajiv Trivedi*, Akella Venkata Subrahmanya Sarma, Balasubramanian Sridhar,Hasitha Shilpa Anantharaju,Dharmarajan Sriram,Perumal Yogeeswari, Narayana Nagesh* Dalton Transactions, 44(40),17600-17616.
39. Design and synthesis of dithiocarbamate linked β-carboline derivatives: DNA topoisomerase II inhibition with DNA binding and apoptosis inducing ability. (2015) Ahmed Kamal*, Manda Sathish, V. Lakshma Nayak, Vunnam Srinivasulu, Botla Kavitha, Yellaiah Tangella, Dinesh Thummuri, Chandrakant Bagul, Nagula Shankaraiah and Narayana Nagesh*. Bioorganic & Medicinal Chemistry, 23, 5511-5526.
38.Biological activities of pyrenyl-derived thiosemicarbazone half-sandwich complexes. (2015) Nandhagopal Raja, Neelakandan Devika, Gajendra Gupta, Vadithe Lakshma Nayak, Ahmed Kamal, Narayana Nagesh*, Bruno Therrien*.Journal of Organometallic Chemistry, 794, 104-114. doi:10.1016/j.jorganchem.2015.06.036.
37. DNA-Binding Affinity and Anticancer Activity of β-Carboline-Chalcone Conjugates as Potential DNA Intercalators: Molecular Modeling and Synthesis.(2015) Nagula Shankaraiah, K. P. Siraj, Shalini Nekkanti, Vunnam Srinivasulu, Pankaj Sharma, Kishna Ram Senwar, Manda Sathish, M. V. P. S. Vishnuvardhan, Sistla Ramakrishna, Chetna Jadala, Narayana Nagesh and Ahmed Kamal. Bioorganic Chemistry, 59, 130–139.
36. A dihydroindolizino indole derivative selectively stabilizes G-quadruplex DNA and down-regulates c-MYC expression in human cancer cells. (2015) Narayana Nagesh*, G. Raju, R. Srinivas, P. Ramesh, M. Damoder Reddy, Ch. Raji Reddy. Biochimica et Biophysica Acta (BBA) - General Subjects, 1850 (1), 129–140.
35. Contribution of cyclin D1 (CCND1) and E-cadherin (CDH1) 5 alterations to colorectal cancer susceptibility : a case-control study. (2014)
Suresh Govatati, Gopi Krishna Singamsetty,Nayudu,Nallabelli,Sravanthi, Malempati, Pasupuleti Sreenivasa Rao,Venkata Kranthi Kumar, Madamchetty, Sowdamani Govatati, Rudramadevi Kanapuram, Nagesh Narayana, Manjula Bhanoori, Kondaiah Kassetty, Varadacharyulu Nallanchakravarthula. Tumor Biology, DOI.10.1007/s13277-014-2505-9.
34. Antiproliferative activities of trithiolato-bridged dinuclear arene osmium complexes. (2014)Gajendra Gupta, Narayana Nagesh, Benjamin S. Murray, Paul J. Dyson, Bruno Therrien. Inorganica Chimica Acta (ICA), 423, 31-35. http://dx.doi.org/10.1016/j.ica.2014.07.050
33.Exploiting Natural Products to Build Metalla Assemblies :The Anticancer Activity of Embelin-Derived Rh(III) and Ir(III)Metalla -Rectangles (2014) Gajendra Gupta, Jerald Mahesh Kumar, Amine Garci, Narayana Nagesh* and Bruno Therrien*.Molecules, 19,6031 -6046. doi:10.3390/molecules
19056031.
32.Incidence of Bcr-Abl kinase domain mutations in imatinib refractory chronic myeloid leukemia patients from South India. (2014) Sailaja Kagita, Srihari Uppalapati, Sangeeta Jiwatani, Vijay Gandhi Linga, Sadasivudu Gundeti, Narayana Nagesh,Raghunadharao Digumarti. Tumor Biology, 13277-014-1926-9, DOI : 10.1007/s
31. Anticancer Activity of Half-Sandwich RhIII and IrIII Metalla-Prisms Containing Lipophilic Side Chains. (2014) Gajendra Gupta, Jerald Mahesh Kumar, Amine Garci, Nandini Rangaraj, Narayana Nagesh*, and Bruno Therrien*, Chempluschem, doi: 10.1002/cplu.201300425.
30.Synthesis of β-carboline-benzimidazole conjugates using lanthanum nitrate as a catalyst and their biological evaluation. (2014) Ahmed Kamal,* M. P. Narasimha Rao, P. Swapna, Vunnam Srinivasulu, Chandrakant Bagul, Anver Basha Shaik, Kishore Mullagiri, Jeshma Kovvuri, K.Vidyasagar and Narayana Nagesh* Organic & Biomolecular Chemistry
29. Studies on non-covalent interaction of coumarin attached pyrimidine and 1-methyl indole 1,2,3 triazole analogues with intermolecular telomeric G-quadruplex DNA using ESI-MS and spectroscopy. (2014) G. Raju, R. Srinivas, M. Damoder Reddy, Ch. Raji Reddy, N. Nagesh*. Nucleosides, Nucleotides and Nucleic Acids.
28. Design and synthesis of C3-pyrazole/chalcone linked β-carboline hybrids: Antitopoisomerase I, DNA interactive and apoptosis inducing anticancer agents.(2014) Ahmed Kamal*, Vunnam Srinivasulu, V. Lakshma Nayak, Manda Sathish, Nagula Shankaraiah, Chandrakant Bagul, N. V. Subba Reddy, Nandini Rangaraj and Narayana Nagesh*. Chemmedchem
27. Pd-Catalyzed Aryl C-H Activation and Tandem ortho-Hydroxylation/Alkoxylation of 2-aryl benzimidazoles: Cytotoxicity and DNA-Binding Studies. (2014) Ahmed Kamal*, Vunnam Srinivasulu, Manda Sathish, Yellaiah Tangella, V. Lakshma Nayak, M. P. Narasimha Rao, Nagula Shankaraiah and Narayana Nagesh*, Asian J. Org. Chem. Vol. 3, Pg. 68 – 76. doi: 10.1002/ajoc.201300214
26. Biological Studies of Chalcogenolato-Bridged Dinuclear Half-Sandwich Complexes.(2013) Justin P Johnpeter, Gajendra Gupta, Jerald Mahesh Kumar, Gunda Srinivas, Narayana Nagesh*, Bruno Therrien*.Inorg. Chem., 52 (23), 13663–13673. doi: 10.1021/ic4022307.
25. Bcl-2 Promoter Sequence G-Quadruplex Interactions with three Planar and Non-planar Cationic Porphyrins: TMPyP4, TMPyP3, and TMPyP2.(2013) Vu H Le, Narayana Nagesh and Edwin A Lewis. PLoS ONE 8(8): e72462. doi:10.1371/journal.pone.0072462.
24.Copper oxide Nanoparticles Supported on Graphene oxide Catalyzed S-Arylation: An Efficient and Ligand free Synthesis of Aryl Sulfides.(2013) Ahmed Kamal, Vunnam Srinivasulu, J.N. S.R. Murty, Nagula Shankaraiah,Narayana Nagesh, T. Srinivasa Reddy, A.V. Subba Rao. Advanced Synthesis and Catalysis, doi: 10.1002/adsc.201300416
23. Phenyl-1,2,3-triazole thymidine ligands stabilize G-quadruplex DNA, inhibit DNA synthesis and potentially reduce tumor cell proliferation over 3'-Azido deoxythymidine. (2013) Jerald Mahesh Kumar, Mohammed M Idris, Gunda Srinivas, Pallerla Vinay Kumar, Vuppalapaty Meghah, Mitta Kavitha, Raji Reddy, Prathama S. Mainkar, Biswajit Pal, Srivari Chadrasekar, Narayana Nagesh*. PLoS ONE 8(8) : e70798. doi:10.1371 /journal. pone.0070798.
22.Production of melanin pigment from Pseudomonas stutzeri isolated from red seaweed Hypnea musciformis. (2013) C. Ganesh Kumar, Nivedita Sahu, G. Narender Reddy, R.B.N. Prasad, Narayana Nagesh, Ahmed Kamal. Letters in Applied Microbiology, doi:10.1111/lam.12111.
21. Interaction of Pyrrolobenzodiazepine (PBD) Ligands with Parallel Intermolecular G-Quadruplex Complex Using Spectroscopy and ESI-MS. (2012) Gajjela Raju, Ragampeta Srinivas, Vangala Santhosh Reddy, Mohammed M. Idris, Ahmed Kamal, Narayana Nagesh*. PLoS ONE, 7 (4) e35920.doi:10.1371 /journal.pone.0035920.
20. Genetic variants of thiopurine and folate metabolic pathways determine 6-MP mediated hematological toxicity in childhood ALL. (2012)
Patchva Dorababu, Shaik Mohammad Naushad, Vijay Gandhi Linga, Sadashivudu Gundeti, Narayana Nagesh, Vijay Kumar Kutala,Pallu Reddanna. Future Medicine-Pharmacogenomics,13(9),1001-1008.
19. Epistatic interactions between Thiopurine methyltransferase (TPMT) and Inosine triphosphate pyrophosphatase (ITPA) variations determine the 6-Mercaptopurine toxicity in Indian children with acute lymphoblastic leukemia. (2011) Patchva Dorababu, Narayana Nagesh, Vijay Gandhi Linga, Sadashivudu Gundeti, Vijay Kumar Kutala, Pallu Reddanna, Raghunadharao Digumarti. European Journal of Clinical Pharmacology. 68:379. doi: 10.1007/s00228-011-1133-1.
18. In situ immobilization of acid protease on mesoporous activated carbon packed column for the production of protein hydrolysates. (2010)
A. Ganesh Kumar, K. Perinbam, P. Kamatchi, N. Nagesh, G. Sekaran. Bioresource Technology.101(4): 1377-1379.
17. Effect of ionic strength on porphyrin drugs interaction with quadruplex DNA formed by the promoter region of C-myc and Bcl2 oncogenes.(2010) Narayana Nagesh*, Varun K. Shar ma, A. Ganesh Kumar,and Edwin A. Lewis. Journal of Nucleic Acids. Article ID 146418,9 pages, doi:10.4061/2010/146418.
16.Influence of fermentation metabolites on redox potential in anaerobic digestion of proteinaceous solid wastes by Synergistes sp. (2010) Arumugam Ganesh Kumar,Ramalingam Kirubagaran,Narayana Nagesh, Juan Parrado Rubio, Ganesan Sekaran.Engineering in Life Sciences. 10(4):1-6.
15. Studies on the site and mode of TMPyP4 interactions with Bcl-2 Promoter Sequence G-quadruplexes. (2010) Narayana Nagesh*, Robert Buscaglia, Jamie M. Dettler and Edwin A. Lewis*. Biophys J. 98 (11): 2628-2633.
14. Synthesis of Readily Accessible Triazole Linked Dimer Deoxynucleoside Phosphoramidite for Solid Phase Oligonucleotide Synthesis.(2010)
Srivari Chadrasekhar, Pabbaraja Srihari,Chidalla Nagesh, Nayani Kiranmay , Narayana Nagesh, M Mohamad Idirs. Synthesis. 21:3710-3714.
13. Purification of extracellular acid protease and analysis of fermentation metabolites by Synergistes sp. utilizing proteinaceous solid waste from tanneries. (2008) A. Ganesh Kumar, N. Nagesh, T.G. Prabhakar, G. Sekaran. Bioresource Technology, 99: 2364-2372.
12. Characterization of an alkaline active - thiol forming extracellular serine keratinase by the newly isolated Bacillus pumilus. (2008) A. Ganesh Kumar, S. Swarnalatha, S. Gayathri, N. Nagesh and G. Sekaran. Journal of Applied Microbiology, 104: 411-419.doi:10.1111 /j.1365-2672.2007. 03564. X
11. Noncovalent Interaction of G-Quadruplex DNA with Acridine at low concentration monitored by MALDI-TOF Mass Spectrometry. (2007)
Narayana Nagesh*, Abburi Krishnaiah, Vishnu Mukund Dhople,Curum S. Sundaram, and Medicharla V. Jagannadham. Nucleosides, Nucleotides and Nucleic Acids., 26: 303-315.
10. A comparative study on the interaction of acridine and syntheticbis-acridine with G-quadruplex structure.(2003) Narayana Nagesh*, Abburi Krishnaiah. J. Biochem. Biophys. Methods, 57:65 –74.
9. Halomonas glacieisp. nov. isolated from fast ice of Adelie Land, Antarctica.(2003) G.S.N. Reddy,P.U.M. Raghavan, N.B. Sarita, J.S.S. Prakash, Narayana Nagesh, Daniel Delille, S. Shivaj. Extremophiles. 7: 55–61. doi: 10.1007/s00792-002-0295-2
8. Was elusive carnivore a panther? DNA typing of faeces reveals the mystery.(2003) Sunil Kumar Verma, Kasturi Prasad, Narayana Nagesh,
Mehar Sultana, Lalji Singh. Forensic Science International. 137 : 16–20.
7. Genetic Locus Encoding Functions Involved in Biosynthesis and Outer Membrane Localization of Xanthomonadin in Xanthomonas oryzae pv. Oryzae. (2002) Ajay Kumar Goel, Lakshmi Rajagopal, Narayana Nagesh, and Ramesh V. Sonti. Journal of Bacteriology. 184(13):3539–3548.
6. A Comparative study on removal of chromium from water effluents by reduction and adsorption over different carbon materials.(2002) Narayana Nagesh* and Abburi Krishnaiah. Indian J Environmental Protection, 22(11), 1221-1225.
5. A useful method for the synthesis of 8 azidoguanosine tri- and tetraphosphate: important substrates for many enzymatic reaction. (1997) Narayana Nagesh, Dipankar Chatterji. J. Biochem.Biophys. Methods.35: 61–66.
4. Ammonium ion at low concentration stabilizes the G-quadruplex formation by telomeric sequence. (1995) Narayana Nagesh, Dipankar Chatterji J. Biochem. Biophys. Methods, 30:1-8.
3. Terbium( III )-Induced Fluorescence of Four-Stranded G4-DNA. (1992) Narayana Nagesh, Purnima Bhargava, Dipankar Chatterji.
Biopolymers. 32: 1421-1424.
2. A study on removal of chromium by adsorption on activated charcoal from synthetic effluents. (1989) Narayana Nagesh and Abburi Krishnaiah. Indian J Environmental Proection, 9(4): 301-303.
1. A study on removal of chromium by adsorption on bituminous coal from synthetic effluents.(1989) Narayana Nagesh and Abburi Krishnaiah. Indian J Environmental Health, 31(4),304-308.
